Tablet



, 25 gram ta lets are made.

Patented Feb. 7, 1928..

STATES PATENT OFFICE.

HEINRICH G'U'NZLER AND OSKAR NEUBERT, OF ELBERFELD, GERMANY, ASSIGNORS T WIN'IHROP CHEMICAL COMPANY, INC, OF NEW YORK, N. Y.

TABLET.

We Drawing. Application filed May 11, 1925, Serial No. 29.618, and in Germany May 22, 1924.

agents e. g. dried sodium sulfate, dried di-.

sodium phosphate etc. These new tablets are more quickly soluble in water than tab-.

1 lets which are prepared from the therapeutically valuable bodies alone or with other suitable additions e. g. sugar, common salt' etc. In addition it is pointed out that acetami-d is not poisonous and has an' agreeable taste. .As it is somewhat hygroscopic it is suitable to add a dehydrating agent as above stated.

In order to illustrate our invention more fully, we give the following examples Ewample 1.--50 parts by weight of the sodium salt of diethylbarbituric acid (veronal) are mixed with 27 parts by weight of acetamid and 3 parts by weight of dry disodium hosphate. From this mixture 0.8 They are clearly soluble in water during 2 minutes.

Emample .@.-50 parts by weight of protein silver (U. S. Letters Patent No. 615,- 970) are mixed together with 63 parts by weight of acetamid and 7 parts by weight of dried sodium sulfate. From this mixture 0.6 gram tablets are prepared. They dissolve in water during one minute furnishing a limpid solution.

Example 8.B0 parts by weight of sodium pyrine are m1 of acetamid. From this mixture 0.8 gram xed with parts by weight tablets are made, being quickly soluble in water.

EwampZe 5.'-30 parts by weight of sodium salt of ethylphenyl barbituric acid are mixed with 15 parts by weight of acetamid.

From this mixture 0.4;5 gram tablets are re very quickly soluble in wamade, 'which a ter.

Example 6'.Tablets which are easily soluble in water can be obtained by mixing 50 parts by weight of dimethylpiperazine tartrate with 50 parts by weight of acetamid.

We claim 1. As an article of manufacture, a tablet, said tablet being a compressed mixture comprising a finely divided water-soluble material and finely divided acetamid;

2. As an article of manufacture, a tablet, said tablet being a compressed mixture comprising a finely divided water-soluble material. finely divided acetamid, and'a finely divided solid dehydrating agent.

In test mony whereof we have hereunto set our hands.

HEINRICH GTTNZLER. OSKAB NEUBERT. 

